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AP

Alnylam Pharmaceuticals, Inc. (ALNY)

NASDAQ • Healthcare

$219.72
-$11.46 (-5.0%)
Market closed

Last close at October 2, 2026 at 20:00 UTC

Open$231.31
Day Range$219.4 - $231.36
Avg. Volume (3M)1.3M
Market Cap$29.4B
P/E Ratio36.0
52 Week Range
$197.81$495.55
Next EarningsIn 25 daysOct 29, 2026

Metrics Over Time

Where the Money Goes

Q2 2026
Revenueeverything earned$1.2B100%
Gross Profitminus cost of goods$992.6M77%
Operating Incomeminus R&D and overhead$231.4M18%
Net Incomeminus taxes and the rest$164.4M13%

In plain terms: out of every $100 in revenue, Alnylam Pharmaceuticals, Inc. keeps $13 as net profit.

Fundamentals & Financials

Revenue (TTM)
$4.8B
Net Income (TTM)
$807.9M
EPS (TTM)
$6.1
ROA (TTM)
14.54%
Current Ratio
3.05

TTM is calculated as the sum of the four most recently completed quarters. This is a standard approach when monthly or real-time data is not available.

Earnings

-29.3%Q1 2026$0.82
+73.2%Q2 2026$1.51
-25.8%Q3 2026$1.21
Next

Oct 29

in 25 daysQ4 2026

% — EPS deviation from the forecast (beat / miss); quarters without a forecast show the reported EPS

Latest report — Q3 2026
Miss -25.8%

Alnylam Pharmaceuticals trailed consensus on both EPS and revenue in the second fiscal quarter of 2026, reported July 30, even as revenue surged year over year. Revenue rose 66.9% to about $1.3 billion (up from roughly $773.7 million a year ago), but revenue of $1.291 billion trailed the $1.322 billion estimate (-2.4%). EPS of $1.21 trailed the $1.63 estimate (-25.8%), improving from -$0.51 a year ago, while net income turned positive to about $164.5 million versus a loss of roughly $66.3 million a year earlier. Profitability tracked with a gross margin near 77% and operating margin around 18%, alongside gross profit of about $992.7 million and operating income of roughly $231.4 million. The company generated operating cash flow of about $75.3 million. Next-period consensus calls for EPS of $2.19 on revenue of $1.429 billion.

Next report — what to expect

Alnylam Pharmaceuticals, Inc. (ALNY) reports next on October 29, 2026. The Street is looking for EPS of $1.77 on revenue of $1.43 billion. As trailing context, revenue rose +66.9% year over year last quarter. ALNY has beaten EPS in 5 of 8 most recent quarters.

View full earnings history

About Alnylam Pharmaceuticals, Inc.

Alnylam Pharmaceuticals, Inc. develops RNA interference medicines in biotechnology and markets treatments for rare diseases, with $3.7 billion in revenue in FY2025. Listed on NASDAQ as ALNY, the company sells ONPATTRO for polyneuropathy associated with hereditary transthyretin-mediated amyloidosis, GIVLAARI for acute hepatic porphyria, and OXLUMO for primary hyperoxaluria type 1.

Name
Alnylam Pharmaceuticals, Inc.
CEO
Yvonne L. Greenstreet
Industry
Healthcare
Year Founded
2002
Employees
2,500

Today's Snapshot

AI-generated

The day ended with ALNY 5% lower at 219.72, while its sector was flat. Volume was about a quarter more than its usual level.

Trading Volume

Above 10d avg 1.2M

1.6M

vs S&P 500 Today

Strong Underperformance

-5.74%

Updated: October 2, 2026 at 20:11 UTC

Technical Indicators

1 Buy1 Neutral6 Sell
ALNY’s technicals present clear bearish pressure: the share price sits well below its short- and long-term moving averages while momentum indicators and MACD are negative, reflecting downward momentum. The CCI and Momentum readings are strongly bearish, even as stochastic and Williams %R register oversold readings, suggesting near-term exhaustion rather than a trend reversal. ADX is low, indicating the downtrend lacks strong directional conviction, while OBV is negative and the classic pivot sits above the market, reinforcing selling bias. Technical takeaway: overall stance is bearish with persistent downside pressure and limited trend strength.
All signals
  • EMA (5 indicators)$241.66 - $310.86
    Sell
  • RSI (14)34.34
    Neutral
  • Stochastic %K (14, 3, 3)18.48
    Buy
  • MACD Level (12, 26)-2.41
    Sell
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