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SE

Septerna Inc (SEPN)

NASDAQ • Healthcare

$37.97
+$0.6 (+1.6%)
Market open

Last close at September 9, 2026 at 20:00 UTC

Open$37.15
Previous Close$37.97
Day Range$37.15 - $39.4
Avg. Volume (3M)424.1K
Market Cap$1.7B
52 Week Range
$13.67$51.1
Next EarningsIn 60 daysNov 9, 2026

Metrics Over Time

Where the Money Goes

Q2 2026
Revenueeverything earned$26.7M100%
Gross Profitminus cost of goods$26.7M100%

In plain terms: out of every $100 in revenue, Septerna Inc currently loses $49.

Fundamentals & Financials

Revenue (TTM)
$98.8M
Net Income (TTM)
-$24.2M
EPS (TTM)
-$0.54
ROA (TTM)
-4.28%
Current Ratio
4.99

TTM is calculated as the sum of the four most recently completed quarters. This is a standard approach when monthly or real-time data is not available.

Earnings

-4.3%Q1 2026-$0.24
+62.7%Q2 2026-$0.19
+31.9%Q3 2026-$0.29
Next

Nov 9

in 60 daysQ4 2026

% — EPS deviation from the forecast (beat / miss); quarters without a forecast show the reported EPS

View full earnings history

About Septerna Inc

Septerna Inc, listed on NASDAQ as SEPN, is a biotechnology company that discovers and develops oral small molecule medicines targeting G protein-coupled receptors. Its work centers on endocrinology, immunology and inflammation, and metabolic disease, and it generated $46.0 million of revenue in FY2025.

Name
Septerna Inc
CEO
Jeffrey T. Finer
Website
septerna.com
Industry
Healthcare
Year Founded
2019
Employees
123

Today's Snapshot

AI-generated

SEPN closed 1.6% higher at 37.97. Wells Fargo, an investment bank, kept its Buy rating and $50 price target for Septerna.

Trading Volume

Above 10d avg 299.0K

475.2K

vs S&P 500 Today

Outperforming Market

+2.09%

Updated: September 10, 2026 at 12:06 UTC

Technical Indicators

4 Buy1 Neutral3 Sell
SEPN is showing a neutral technical profile as momentum and trend signals are mixed. Short-term momentum is soft—momentum and MACD register modest downside while RSI sits near the middle—yet the stock remains above its 50‑ and 200‑day averages, indicating longer-term support. ADX near the high teens implies little directional conviction, and ATR near two dollars signals moderate intraday volatility consistent with range trading. Volume-based OBV reads weak, which tempers the moving-average support, and the price sits close to the classic pivot around thirty-seven dollars. Technical takeaway: Neutral.
All signals
  • EMA (5 indicators)$30.32 - $38.91
    Buy
  • RSI (14)46.44
    Neutral
  • Stochastic %K (14, 3, 3)14.81
    Buy
  • MACD Level (12, 26)-0.34
    Sell

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